Causes and diagnosis and management of acute convulsions

Saturday, May 5, 20120 comments


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Causes and diagnosis and management of acute convulsions IN simple way  now you can recognize it in any time just read this note and you will know .

Causes:
a- Non-febrile convulsions:
  •  Toxic:
  • Hypoxic:
  1. - Convulsant drugs: aminophylline, steroids.
  2. - Bacterial toxins: tetanus, salmonella.
  3. - Poisoning: CO, lead, organophosphrous
  4. - Post – kernicterus.
  5. - Asphyxia neonatorum.
  6. - Cyanotic spells (congenital heart diseases.)
  •  Ischemic:
  1. - Cerebral thrombosis ( S.C. anemia )
  2. - Intra cranial hemorrhage.
  3. - Cerebral embolism.
  •  Metabolic:
  1. - Ca - Mg ( tetany + inborn error of metabolism )
  • Brain:
  1. Infection: - Vital: encephalitis, polio enceph.
  2. Bacterial: meningitis, Brian abscess.
  3. Injury: Trauma
  4. Edema: AGN. - Tumors.
  5. Nutritional: hypoglycemia – Vit. B6 deficiency.
  6. Idiopatihic or familial.
  7. ICH (trauma, hypoxic ischemic , encephalopathy)
B- febrile convulsions:
  1. High environmental temperature.
  2. Extra – cranial infection ( CVS , Chest , GIT , urinary ).

Diagnosis:
1- History: * Onset: ( acute – chronic ).
* Of the cause: head trauma – infection – congenital heart diseases.
2- Full neurological exam: to decide if cranial or extra-cranial.
3- Investigations:
  • X-ray, CT, MRI.
  • CSF analysis.
  • Blood exam.
  • Urine analysis.
  • ECG, ECHO, EEG.
Treatment:
I- During seizure:
a- Air way: keep patent by:
  • Semiprone position with head down & to the right.
  • Suction of secretions.
  • Mouth gag.
  • Tongue depressor.
b- O2 therapy.
c- Anti-convulsant drugs: IV. Diazepam also, rectal effective ( 1 / 2 gm / kg ).
d- Symptomatic ttt: fever – anti-pyretics acetaminophen + cold fomentation.
e- Underlying cause ttt: infection antibiotic & hypoglycemia, IV glucose 10 %.
II- Long term management: ( Prophylaxis of recurrence )
  • Continuous prophylaxis : about one year phenobarbitone.
  • Intermittent prophylaxis : diazepam at onset of fever.
N.B.: Simple febrile convulsions is benign not has long term sequale – not need prophylaxis
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