Diagnostic criteria for Systemic Lupus Erythematosus
Systemic lupus erythematosus is a chronic inflammatory autoimmune disorder which may affect many organ systems including the skin, joints and internal organs.
The disease may be mild or severe and life-threatening.
African-Americans and Asians are disproportionately affected.
Lupus is diagnosed based on a combination of clinical signs such and specific blood test abnormalities.
The most common autoantibody seen in lupus is the antinuclear antibody (ANA).
Current diagnostic criteria for SLE include 4 of the following symptoms to be present at any time during a patient's history:
· Malar rash
· Discoid rash
· Oral ulcers
· Arthritis : peripheral arthritis
· Renal disorder : proteinuria
· Neurologic disorder : psychosis
· Hematologic disorder : pancytopenia
· Immunologic disorder
· Antinuclear antibody